A pessary is a soft, flexible device that is inserted into the vagina to support pelvic structures such as the bladder, uterus, and rectum and to prevent their protrusion into the vagina. They are made in a variety of shapes and sizes and can be an effective, non-invasive way to treat pelvic organ prolapse. Different forms of pessary have been used since ancient times, including a reference by Hippocrates in which half a pomegranate was used to support a prolapsed uterus. By the 16th century, pessaries were commonly made by dipping a ball of string into wax. It was only when vulcanized rubber was discovered in the 19th century that pliable pessaries were manufactured on a production scale.
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Androgens are a group of hormones that play a role in male traits and reproductive activity. Present in both males and females, the principle androgens are testosterone and androstenedione. Androgens may be called "male hormones," but don't let the name fool you. Both men's and women's bodies produce androgens, just in differing amounts. In fact, androgens have more than actions in women, and they are present in higher amounts than estrogens.
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What to Expect Along the Path to Conceiving With IVF
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Diethylstilbestrol DES is a synthetic form of the female hormone estrogen. It was prescribed to pregnant women between and to prevent miscarriage, premature labor, and related complications of pregnancy 1. The use of DES declined after studies in the s showed that it was not effective in preventing these problems. In , researchers linked prenatal before birth DES exposure to a type of cancer of the cervix and vagina called clear cell adenocarcinoma in a small group of women 2. The drug continued to be prescribed to pregnant women in Europe until 4.